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Alexander had also established several colonies in neighbouring Bactria, such as Alexandria on the Oxus (modern Ai-Khanoum) and Alexandria of the Caucasus (medieval Kapisa, modern Bagram).After Alexander's death in 323 BC, Bactria came under the control of Seleucus I Nicator, who founded the Seleucid Empire.
The confrontation ended with a peace treaty, and "an intermarriage agreement" (Epigamia, Greek: Ἐπιγαμία), meaning either a dynastic marriage or an agreement for intermarriage between Indians and Greeks.
The Greeks in the Indian Subcontinent were eventually divided from the Graeco-Bactrians centered in Bactria (now the border between Afghanistan and Uzbekistan), and the Indo-Greeks in the present-day north-western Indian Subcontinent.
The most famous Indo-Greek ruler was Menander (Milinda).
but since the extensive sources available on Seleucus never mention an Indian princess, it is thought that the marital alliance went the other way, with Chandragupta himself or his son Bindusara marrying a Seleucid princess, in accordance with contemporary Greek practices to form dynastic alliances. From him, Vindusara was born and ruled for the same number of years as his father.
An Indian Puranic source, the Pratisarga Parva of the Bhavishya Purana, described the marriage of Chandragupta with a Greek ("Yavana") princess, daughter of Seleucus, "Chandragupta married with a daughter of Suluva, the Yavana king of Pausasa. His son was Ashoka." On these occasions, Greek populations apparently remained in the northwest of the Indian subcontinent under Mauryan rule.
After 321 BC Eudemus toppled Taxiles, until he left India in 316 BC.